Used to express that something is true regardless of the circumstances, similar to 不管 bù​guǎn or 无论 wú​lùn.

no matter what or how; regardless of, used to show that a condition does not change the outcome

To let something happen, to give free rein to, or to listen to someone's whim.

to rely on; to depend on; to use one's status or strength to achieve something