in any case; at any rate; no matter what; by all possible means

used to ask for someone's opinion or suggestion; how about it?

To have no way out or no way to solve a situation; describes a situation that is already settled and cannot be changed. Same as [[无可奈何|無可奈何|wu2 ke3 nai4 he2]].

what should one do; what's the best way to handle this. Often used to express feeling helpless or at a loss in a difficult situation. situation