completely irrelevant or mismatched; often describes a response that has nothing to do with the question asked

literally meaning "a donkey's lips do not match a horse's mouth"; used to describe things that are completely irrelevant to each other, wide of the mark, or a reply that does not answer the question

Tsushima Island, located in the Korea Strait between Japan and South Korea

the Tsushima Strait located between Japan and South Korea

ox's head doesn't match horse's face; inconsistent or irrelevant to the point at hand