to do something with all one's heart and might; to make an all-out effort

to rack one's brains for schemes; to try every possible means or plot to achieve an end

(idiom) to put one's heart and soul into something; to do something with extreme care and diligence

To try every possible means or tax one's ingenuity to the limit in order to achieve a goal

to exhaust one's heart and soul; to pour all of one's energy and thought into something

to rack one's brains; to take great pains to think something through or find a way to do something

to do one's utmost; to devote all of one's mind and heart to a task

to have experienced one's full share of sorrows and hardships; to have tasted all the bitterness that life has to offer