to work diligently and struggle hard in spite of difficult conditions or the spirit of such perseverance

extremely difficult and grueling; used to describe a struggle or task that is exceptionally hard and surpasses all others

to be hardworking and live a simple, frugal life; characterizes a person who can endure hardship and avoids extravagance

To have experienced every kind of difficulty and suffering.

to have experienced great difficulties and bitterness; to have undergone all kinds of trials and tribulations