noun · Colloquial name for a German shepherd dog.

那家工厂的大院里拴着一只凶猛的二毛子。

noun · A derogatory term for a person of mixed Chinese and Russian heritage.

他有一半俄罗斯血统，因此被一些人叫做二毛子。

proper name · A derogatory term for Chinese Christians or those associated with foreigners (historical), or a colloquial term for a westernized Chinese person.

在义和团运动中，信奉洋教的中国人常被蔑称为二毛子。

noun · A dialect term for a goat that has reached two years of age.

这只二毛子的羊毛质量非常好。

noun · Modern Chinese internet slang for Ukraine.

网友们常把俄罗斯称为大毛，把乌克兰称为二毛子。