adjective · to be in an unfavorable position or at a disadvantage due to certain circumstances

他身材矮小，打篮球比较吃亏。

adjective · to suffer financial or personal losses, to lose out, or to be taken advantage of

他宁可自己吃亏，也不愿让朋友受损失。

adjective · to be at a disadvantage or suffer because of a specific factor; often used as 'the trouble is...'

这孩子挺聪明，就是吃亏在不肯用功。