noun · the specific skill, style, or hand of a writer, calligrapher, or painter

这篇文章手笔雄健，读来令人振奋。

noun · something written or painted in one's own hand

这幅字画是苏东坡的亲笔手笔。

noun · the manner or scale shown in spending money or handling business affairs

他在慈善事业上的投入真可谓是大手笔。