verb · to distance oneself from someone or to cause someone to become estranged

他这种傲慢的态度会疏远他身边的朋友。

verb · to become less close or emotionally distant in a relationship

毕业以后，我们之间的关系渐渐疏远了。

verb · the state of being distant or the loss of intimacy in a relationship

长期的疏远让他们的感情变得越来越淡。