utterly defeated, ruined, or devastated, often used in the context of a family's fortunes, a country, or an organization

经过长年的战乱，这个曾经繁荣的国家变得破败不堪。

in a state of total ruin, decay, or extreme disrepair, typically describing buildings or places

由于多年无人居住且缺乏维护，这座老宅已经破败不堪。