to establish oneself independently, often by setting up a separate household or career

许多年轻人结婚后都希望自立门户，搬出去独立生活。

expression · to form one's own group, faction, or school of thought

这位艺术家在传统技法的基础上自立门户，形成了独特的艺术风格。

to set up one's own business or professional practice

在这个行业工作多年后，他决定辞职自立门户，开一家自己的咨询公司。