4 sentences

1. 面对困难，他丝毫不退缩。

   miàn​duì kùn​nan, tā sī​háo bù tuì​suō.

   He didn't flinch at all in the face of difficulties.

   Source: Dong Chinese Dictionary

2. 情况丝毫没有改变。

   qíng​kuàng sī​háo méi​yǒu gǎi​biàn.

   The situation hasn't changed at all.

   Source: Tatoeba

3. 即使面对困难，他也丝毫不退缩。

   jí​shǐ miàn​duì kùn​nan, tā yě sī​háo bù tuì​suō.

   Even in the face of difficulties, he didn't flinch in the slightest.

   Source: Dong Chinese Dictionary

4. 我们要抓紧生产安全，不能有丝毫马虎。

   wǒ​men yào zhuā​jǐn shēng​chǎn ān​quán, bù néng yǒu sī​háo mǎ​hu.

   We must focus on production safety and cannot afford to be careless.

   Source: Dong Chinese Dictionary