3 sentences

1. 抗议者将愤怒直指制药公司。

   kàng​yì zhě jiāng fèn​nù zhí​zhǐ zhì​yào gōng​sī.

   Protestors directed their anger at pharmaceutical companies.

   Source: OpenSubtitles

2. 他的文章用词锋利，直指社会问题的核心。

   tā de wén​zhāng yòng​cí fēng​lì, zhí​zhǐ shè​huì wèn​tí de hé​xīn.

   His articles use sharp language, pointing directly to the core of social issues.

   Source: Dong Chinese Dictionary

3. 他的讲话非常有针对性，直指问题的核心。

   tā de jiǎng​huà fēi​cháng yǒu zhēn​duì​xìng, zhí​zhǐ wèn​tí de hé​xīn.

   His speech was very targeted, striking directly at the core of the problem.

   Source: Dong Chinese Dictionary